Ignite Creation Date:
2025-12-24 @ 11:52 AM
Ignite Modification Date:
2025-12-26 @ 7:23 AM
Study NCT ID:
NCT00005761
Status:
COMPLETED
Last Update Posted:
2017-07-02
First Post:
2000-05-26
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Blood Factors and Diabetic Retinopathy
Sponsor:
National Eye Institute (NEI)
Organization:
Study Overview
Official Title:
Study of Association of Serum Factors With Diabetic Retinopathy
Status:
COMPLETED
Status Verified Date:
2010-12-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will determine whether certain factors in the blood are associated with the severity of diabetic retinopathy.
Patients age 10 years and older with diabetes mellitus and diabetic retinopathy may be eligible for this study. Those enrolled will represent a range of diabetic retinopathy from minimal to severe. Participants will undergo the following procedures:
* medical history
* thorough eye examination
* photographs of the eye
* blood tests to measure blood lipids (cholesterol and triglycerides) and serum creatinine (for kidney function)
* blood tests to measure levels of blood factors (cell adhesion molecules, chemokines and vascular endothelial growth factor) that may be related to the progression of diabetic retinopathy
* blood pressure measurement
* urinalysis
This study may lead to a better understanding of how diabetic retinopathy develops and progresses.
Patients age 10 years and older with diabetes mellitus and diabetic retinopathy may be eligible for this study. Those enrolled will represent a range of diabetic retinopathy from minimal to severe. Participants will undergo the following procedures:
* medical history
* thorough eye examination
* photographs of the eye
* blood tests to measure blood lipids (cholesterol and triglycerides) and serum creatinine (for kidney function)
* blood tests to measure levels of blood factors (cell adhesion molecules, chemokines and vascular endothelial growth factor) that may be related to the progression of diabetic retinopathy
* blood pressure measurement
* urinalysis
This study may lead to a better understanding of how diabetic retinopathy develops and progresses.
Detailed Description:
Participants with a range of severity of diabetic retinopathy and healthy volunteers will be evaluated once for serum levels of cell adhesion molecules, chemokines and vascular endothelial growth factor. This study may lead to a better understanding of the pathogenesis of diabetic retinopathy and the identifying of possible targets for treatment. All study participants will undergo an ocular exam and ophthalmic photography. Blood is drawn for the analysis of these serum factors.
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| 00-EI-0135 | None | None | View |