Ignite Creation Date:
2024-05-05 @ 7:28 PM
Last Modification Date:
2024-10-26 @ 9:49 AM
Study NCT ID:
NCT00678028
Status:
COMPLETED
Last Update Posted:
2009-04-23
First Post:
2008-02-17
Brief Title:
Association Between Deficiency of MBL Mannose-Binding Lectin and Polymorphisms in MBL2 Gene to Urinary Tract Infection
Sponsor:
HaEmek Medical Center Israel
Organization:
HaEmek Medical Center Israel
Study Overview
Official Title:
Association Between Deficiency of MBL Mannose-Binding Lectin and Polymorphisms in MBL2 Gene to Urinary Tract Infection
Status:
COMPLETED
Status Verified Date:
2009-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Due to genetic polymorphism about 15-30 of the world population have low levels of MBL Mannose Binding Lectin in serum below 500ngmL Different studies reported correlation between polymorphism in the MBL gene with low levels of MBL in serum and higher frequency of recurrent infections severity of sepsis ARDS and other infections Urinary Tract Infection UTI is one of the very common infection in women Since MBL is part of the innate immunity and there are proofs of relation between patients with recurrent infections and lack of MBL we decided to explore a possible relation between low levels of MBL and different genotypes of MBL in young women and the risk to develop recurrent UTI
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None