Ignite Creation Date:
2024-05-05 @ 7:28 PM
Last Modification Date:
2024-10-26 @ 9:49 AM
Study NCT ID:
NCT00676416
Status:
COMPLETED
Last Update Posted:
2009-03-31
First Post:
2008-05-08
Brief Title:
Influence of Propofol on Alveolar Macrophage in Asthmatic Patients
Sponsor:
Nanjing Medical University
Organization:
Nanjing Medical University
Study Overview
Official Title:
Influence of Propofol on Alveolar Macrophage Immunity in Asthmatic Patients Undergoing General Anesthesia
Status:
COMPLETED
Status Verified Date:
2009-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PAMAP
Brief Summary:
The change of airway responsiveness and alveolar macrophage AM immunity occurs during the pathogenesis of asthma Macrophage-associated airway protection in patients with asthma is affected positively or negatively by propofol general anesthesia The investigators hypothesized that the effects of propofol on asthmatic AMs and corresponding airway reactivity in vivo is different from the in vitro research Through in vivo airway hyperresponsiveness AHR observation and clinical investigation of AM immune functions from asthma patients undergoing propofol general anesthesia to clarify the precise effects of propofol on AM immunity and to provide theoretical basis for the clinical administration of propofol in asthmatic patients This would optimize the practice of clinical anesthesia especially for those with the tendency of AHR
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NMU-08-1090 | None | None | None |