Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:03 AM
Study NCT ID:
NCT00003045
Status:
COMPLETED
Last Update Posted:
2017-04-26
First Post:
1999-11-01
Brief Title:
Hyperthermia Plus Radiation Therapy in Treating Patients With Nonmetastatic Advanced Prostate Cancer
Sponsor:
Dana-Farber Cancer Institute
Organization:
Dana-Farber Cancer Institute
Study Overview
Official Title:
A Phase II Trial of Hyperthermia and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate
Status:
COMPLETED
Status Verified Date:
2017-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hyperthermia therapy may kill prostate cancer cells by heating them to several degrees above body temperature Radiation therapy uses high-energy x-rays to damage tumor cells Combining hyperthermia with radiation therapy may kill more tumor cells
The purpose of this study is to determine the ability of hyperthermia when combined with radiation therapy and in some patients hormonal therapy to control prostate cancer
The purpose of this study is to determine the ability of hyperthermia when combined with radiation therapy and in some patients hormonal therapy to control prostate cancer
Detailed Description:
The purpose of this study is to determine the ability of hyperthermia heat treatments produced by sound waves when combined with radiation therapy and in some patients hormonal therapy to control prostate cancer
Hyperthermia refers to the use of temperatures 42 oC 107-6oF or higher to treatment malignant tumors Laboratory and some clinical reports have demonstrated a tumor killing effect if tumors are heated to 43oC 109oF for 30-60 minutes
Many studies have shown that hyperthermia improves the killing effect of radiation treatments for many tumors In clinical studies the addition of hyperthermia has shown to be beneficial for tumors of the breast urinary bladder and the head and neck region with combined with radiation therapy Investigators found an improvement in tumor response rates and a lengthened duration of response The proposed study is one of the first controlled studies to attempt to prove the usefulness of hyperthermia for patients with prostate cancer
Hyperthermia refers to the use of temperatures 42 oC 107-6oF or higher to treatment malignant tumors Laboratory and some clinical reports have demonstrated a tumor killing effect if tumors are heated to 43oC 109oF for 30-60 minutes
Many studies have shown that hyperthermia improves the killing effect of radiation treatments for many tumors In clinical studies the addition of hyperthermia has shown to be beneficial for tumors of the breast urinary bladder and the head and neck region with combined with radiation therapy Investigators found an improvement in tumor response rates and a lengthened duration of response The proposed study is one of the first controlled studies to attempt to prove the usefulness of hyperthermia for patients with prostate cancer
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NCI-H97-1294 | US NIH GrantContract | None | httpsreporternihgovquickSearchP30CA006516 |
| P30CA006516 | NIH | None | None |