Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00007397
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-12-19
Brief Title:
Age Risk Factors for CVD and Cognitive Functioning
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2005-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To relate cardiovascular disease CHD risk factors to cognitive performance among middle-aged and elderly men and women over a 10 year longitudinal study period
Detailed Description:
BACKGROUND
The Framingham Heart Study is a major epidemiological investigation of prospective relationships between risk factors for the development of cardiovascular disease CVD risk factors and CVD risk factor outcomes The Framingham Study and other large prospective studies have resulted in an extensive literature on the impact of CVD risk factors including age and CVD outcomes Comparatively there have been many fewer studies of the impact of CVD risk factors on cognitive functioning and possibly no studies of the effect of objectively measured competing risk factors on cognitive functioning
DESIGN NARRATIVE
Dr Elias and colleagues used cardiovascular risk factor data from the Framingham Heart Study N 2123 in a prospective design allowing them to relate CVD risk factors including age and gender to two outcome measures 1 level of cognitive performance and 2 change in cognitive performance over a 10 year longitudinal study period The overall goals were to determine the best multivariate combination of biological and psychosocial risk factors for the prediction of lowered cognitive ability in middle-aged and elderly men and women and to evaluate the relative impact of age gender and other biological and psychosocial risk factors on cognitive functioning
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
The Framingham Heart Study is a major epidemiological investigation of prospective relationships between risk factors for the development of cardiovascular disease CVD risk factors and CVD risk factor outcomes The Framingham Study and other large prospective studies have resulted in an extensive literature on the impact of CVD risk factors including age and CVD outcomes Comparatively there have been many fewer studies of the impact of CVD risk factors on cognitive functioning and possibly no studies of the effect of objectively measured competing risk factors on cognitive functioning
DESIGN NARRATIVE
Dr Elias and colleagues used cardiovascular risk factor data from the Framingham Heart Study N 2123 in a prospective design allowing them to relate CVD risk factors including age and gender to two outcome measures 1 level of cognitive performance and 2 change in cognitive performance over a 10 year longitudinal study period The overall goals were to determine the best multivariate combination of biological and psychosocial risk factors for the prediction of lowered cognitive ability in middle-aged and elderly men and women and to evaluate the relative impact of age gender and other biological and psychosocial risk factors on cognitive functioning
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R43HL065117 | NIH | None | httpsreporternihgovquickSearchR43HL065117 |