Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:01 AM
Study NCT ID:
NCT00000106
Status:
UNKNOWN
Last Update Posted:
2005-06-24
First Post:
2000-01-18
Brief Title:
418 Degree Centigrade Whole Body Hyperthermia for the Treatment of Rheumatoid Diseases
Sponsor:
National Center for Research Resources NCRR
Organization:
National Center for Research Resources NCRR
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2000-11
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Recently a non-toxic system for whole body hyperthermia WBH used at the University of Wisconsin has been shown to induce soluble tumor necrosis factor-receptor sTNF-R I and II when patients are heated systemically to 418C for 60 minutes This observation might provide a biological basis for the therapeutic application of WBH to rheumatoid diseases for which there is a positive anecdotal clinical experience Inherent in the hypothesis which is the basis for this protocol is the concept that the induction of TNF receptors by WBH may induce a remission in patients with active rheumatoid arthritis Beyond clinical response the biological endpoint for this investigation includes cytokine levels TNF levels sTNF-R levels and changes in cellular TNF receptors
Detailed Description:
None
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| M01RR003186 | NIH | None | httpsreporternihgovquickSearchM01RR003186 |