Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005492
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-05-25
Brief Title:
Pooled Analysis of NHANES III--Race Gender and CHD
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2005-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To conduct a pooled analysis of NHANES III data on race gender and coronary heart disease
Detailed Description:
BACKGROUND
Over the last 25 years a sustained and marked decline in death rates from coronary heart disease CHD has occurred for all major segments of the US population Recently however the decline has proceeded less rapidly in blacks than in whites and in women than men These trends have focused further attention on possible heterogeneity in the risk factor patterns among the demographic sub-groups Previous studies of CHD risk factors in blacks and whites using the First National Health and Examination Survey Epidemiologic Follow-up Study NHEFS-I 11-year follow-up including this groups own work demonstrate its potential strengths while at the same time foundering on the problem of low statistical power With the extension of the follow-up of NHANES-I cohort 1971-1974 to 1987 14 years and the completion of 14-year follow-up for NHANES II cohort 1976-1980 a strong rationale exists to undertake a pooling project The resulting data set would provide optimal characterization of CHD risk at the national level
DESIGN NARRATIVE
The study sought to determine whether data from NHANES I and NHANES II could be pooled To accomplish this the distribution of baseline measures was assessed and a determination was made whether the same logistic prediction equations fitted both studies Also gender-race differences were examined in individual exposure-outcome relationships patterns of co-morbidity and population attributable risks
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Over the last 25 years a sustained and marked decline in death rates from coronary heart disease CHD has occurred for all major segments of the US population Recently however the decline has proceeded less rapidly in blacks than in whites and in women than men These trends have focused further attention on possible heterogeneity in the risk factor patterns among the demographic sub-groups Previous studies of CHD risk factors in blacks and whites using the First National Health and Examination Survey Epidemiologic Follow-up Study NHEFS-I 11-year follow-up including this groups own work demonstrate its potential strengths while at the same time foundering on the problem of low statistical power With the extension of the follow-up of NHANES-I cohort 1971-1974 to 1987 14 years and the completion of 14-year follow-up for NHANES II cohort 1976-1980 a strong rationale exists to undertake a pooling project The resulting data set would provide optimal characterization of CHD risk at the national level
DESIGN NARRATIVE
The study sought to determine whether data from NHANES I and NHANES II could be pooled To accomplish this the distribution of baseline measures was assessed and a determination was made whether the same logistic prediction equations fitted both studies Also gender-race differences were examined in individual exposure-outcome relationships patterns of co-morbidity and population attributable risks
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R03HL058436 | NIH | None | httpsreporternihgovquickSearchR03HL058436 |