Ignite Creation Date:
2024-05-05 @ 11:22 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005125
Status:
COMPLETED
Last Update Posted:
2015-06-03
First Post:
2000-05-25
Brief Title:
NAS-NRC Twin Registry
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2001-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To continue a registry of World War II veteran twins maintained by the National Academy of Sciences-National Research Council NAS-NRC
Detailed Description:
BACKGROUND
The registry of World War II veteran twins came into existence in the late 1960s through a search and link effort of state vital statistics records and Veterans Administration files through the Medical Follow-up Agency of NAS-NRC Since that time the registry has served as a data resource for investigators in a variety of scientific fields who want to study genetic and environmental aspects of various human characteristics Because of the size and geographic coverage throughout the United States the registry offers a method of recruiting sizeable numbers of twins for study even under geographic restrictions Of special value to medical researchers is the built-in medical follow-up for morbidity and mortality through Veterans Administration insurance and benefits records This allows researchers to gather baseline data which may be related prospectively to morbidity and mortality events
The NHLBI has made extensive use of the World War II veteran twin registry beginning in 1969 when the NHLBI Twin Study was initiated At that time NHLBI used the World War II veteran twin registry to recruit a group of 514 pairs of twins in five geographic areas to participate in a study which included a battery of questionnaires and a physical examination Since that time a second examination and third examination of the cohort have been completed and the registry has been used to maintain contact with the twins and provide surveillance for morbidity and mortality events of the participants in the study
DESIGN NARRATIVE
Maintenance of the existing registry continued as addresses of all members were updated annually as well as morbidity and mortality data through surveillance of Veterans Administration insurance and death benefit records or through the National Death Index All morbid events and deaths were coded by ICD codes Support activities were provided for the NHLBI Twin Study including providing death certificates for events occurring among the 1028 twins participating in the study and mailed questionnaire follow-up
Although contract support ended in September 1988 analyses of the survey and mortality data are continuing
The registry of World War II veteran twins came into existence in the late 1960s through a search and link effort of state vital statistics records and Veterans Administration files through the Medical Follow-up Agency of NAS-NRC Since that time the registry has served as a data resource for investigators in a variety of scientific fields who want to study genetic and environmental aspects of various human characteristics Because of the size and geographic coverage throughout the United States the registry offers a method of recruiting sizeable numbers of twins for study even under geographic restrictions Of special value to medical researchers is the built-in medical follow-up for morbidity and mortality through Veterans Administration insurance and benefits records This allows researchers to gather baseline data which may be related prospectively to morbidity and mortality events
The NHLBI has made extensive use of the World War II veteran twin registry beginning in 1969 when the NHLBI Twin Study was initiated At that time NHLBI used the World War II veteran twin registry to recruit a group of 514 pairs of twins in five geographic areas to participate in a study which included a battery of questionnaires and a physical examination Since that time a second examination and third examination of the cohort have been completed and the registry has been used to maintain contact with the twins and provide surveillance for morbidity and mortality events of the participants in the study
DESIGN NARRATIVE
Maintenance of the existing registry continued as addresses of all members were updated annually as well as morbidity and mortality data through surveillance of Veterans Administration insurance and death benefit records or through the National Death Index All morbid events and deaths were coded by ICD codes Support activities were provided for the NHLBI Twin Study including providing death certificates for events occurring among the 1028 twins participating in the study and mailed questionnaire follow-up
Although contract support ended in September 1988 analyses of the survey and mortality data are continuing
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?: