Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06656819
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-21
Brief Title:
The Modulatory Effect of Female Sex Hormones on Spinal Neuroplasticity
Sponsor:
None
Organization:
None
Study Overview
Official Title:
TMSpine the Modulatory Effect of Female Sex Hormones on Spinal Neuroplasticity
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TMSpine
Brief Summary:
The goal of this project is to test our central hypothesis that the spinal cord neuroplasticity in females will be modulated by the level of estradiol concentration under aim 1 we will determine the influence of estradiol fluctuations on spinal circuit excitability post afferent sensory mediated subthreshold motor priming in young healthy females and males We will use an established repetitive peripheral nerve electrical stimulation with a stimulation intensity below the motor threshold to prime the spinal motor circuits under aim 2 we seek to characterize the input output property of spinal circuit excitability after descending drive motor mediated priming in young healthy male participants in aim 3 we will examine the influence of estradiol fluctuations on descending drive mediated motor priming in young healthy females
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None