Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06655909
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-10-22
Brief Title:
Serum Ferritin Concentration in Kenyan Women and Their Preschool Children At Which the Body Begins to Upregulate Iron Absorption from the Diet
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Defining the Serum Ferritin Concentration in Kenyan Women and Their Preschool Children At Which the Body Senses Iron Depletion and Begins to Upregulate Iron Absorption from the Diet
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Using standardized methods our laboratory will perform stable iron isotope absorption studies in young Kenyan women and their preschool children 2-5y of age with varying iron status to measure iron absorption from maize meal containing labeled ferrous sulfate Using these data our study aim is to define the ferritin in these young women and children at which the body senses iron depletion and begins to upregulate iron absorption from the diet this approach could provide a functionally defined threshold of iron deficiency in Sub-Saharan African women and children
Detailed Description:
In this experimental study in southern Kenya we will take a baseline venous blood sample to measure iron and inflammation biomarkers in generally healthy young women n125 and in their preschool children We will then administer after an overnight fast a standardized test meal porridge made from refined maize and bottled water containing the stable iron isotope 57Fe Fourteen days later we will take a second venous blood sample for determination of erythrocyte incorporation of the 57Fe to measure iron absorption from the labeled test meal
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None