Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06653439
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-20
Brief Title:
Analgesic Effect of Bilateral Subcostal Quadratus Lumborum Block in Laparoscopic Colorectal Surgery
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Analgesic Effect of Ultrasound-Guided Bilateral Subcostal Anterior Quadratus Lumborum Block in Laparoscopic Colorectal Surgery A Randomized Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Effective postoperative pain management is crucial for promoting early recovery and ambulation following laparoscopic colorectal surgery Regional anesthesia techniques like interfascial plane blocks are increasingly being used to achieve this The quadratus lumborum block QLB is a relatively new approach in abdominal surgeries providing significant pain relief by blocking both somatic and sympathetic nerves In particular the anterior QLB technique allows local anesthetic to spread to the thoracic paravertebral space making it potentially more effective for postoperative analgesia The hypothesis of this study is that bilateral subcostal anterior QLB can reduce both postoperative pain and opioid consumption in laparoscopic colorectal surgery
Detailed Description:
Postoperative pain management is a critical factor in enhancing recovery and ambulation following laparoscopic colorectal surgery Effective analgesia is necessary to reduce complications improve patient comfort and shorten hospital stays In this context multimodal analgesia is a commonly used strategy that combines various analgesic drugs such as paracetamol nonsteroidal anti-inflammatory drugs NSAIDs and opioids to manage pain more effectively by targeting different pathways
Although opioids are considered the gold standard for postoperative pain control their use is associated with several undesirable side effects including nausea vomiting dizziness constipation and respiratory depression These opioid-related complications can delay recovery increase patient discomfort and extend hospital stays Therefore minimizing opioid consumption while still providing effective pain relief is a primary goal in postoperative pain management particularly for surgeries such as laparoscopic colorectal procedures
To achieve this goal regional anesthesia techniques have gained increasing popularity These techniques such as interfascial plane blocks have the potential to reduce opioid use and improve pain control by targeting specific nerve pathways One of the more recent approaches is the quadratus lumborum block QLB which involves the injection of local anesthetics near the quadratus lumborum muscle This block is particularly useful in abdominal surgeries because it can provide pain relief by affecting both somatic and sympathetic nerves leading to broader and more effective pain coverage
The QLB has four different approaches anterior lateral posterior and intramuscular The anterior QLB is of particular interest in this setting because it involves the injection of local anesthetic between the quadratus lumborum and psoas muscles potentially allowing the anesthetic to spread into the thoracic paravertebral space This spread could result in the blockade of both the somatic nerves and the thoracic sympathetic chain offering more comprehensive pain relief that is beneficial for abdominal surgeries like colorectal procedures
The potential advantages of the anterior QLB in laparoscopic colorectal surgery include reduced postoperative pain decreased opioid consumption and fewer opioid-related side effects Additionally regional anesthesia techniques like QLB may reduce postoperative complications including respiratory issues which are particularly important in abdominal surgeries that involve the diaphragm and lower thoracic nerves
In this study the hypothesis is that bilateral subcostal anterior QLB administered during laparoscopic colorectal surgery will significantly reduce both postoperative pain and the need for opioids
The aim of this study is to investigate the effects of Bilateral subcostal anterior QLB on postoperative acute pain scores 0-24 hours and 24- hour opioid consumption in patients who underwent laparoscopic colorectal surgery Our study which the investigators think will contribute to the literature was planned as a prospective randomized controlled parallel-group study
Patients will be divided into two groups
Group S-QLB
A bilateral S-QLB 40 ml 025 bupivacaine 1400000 adrenaline will be performed In addition IV morphine-PCA will be applied postoperatively for 24 hours
Group Control
IV morphine-PCA will be applied postoperatively for 24 hours
Although opioids are considered the gold standard for postoperative pain control their use is associated with several undesirable side effects including nausea vomiting dizziness constipation and respiratory depression These opioid-related complications can delay recovery increase patient discomfort and extend hospital stays Therefore minimizing opioid consumption while still providing effective pain relief is a primary goal in postoperative pain management particularly for surgeries such as laparoscopic colorectal procedures
To achieve this goal regional anesthesia techniques have gained increasing popularity These techniques such as interfascial plane blocks have the potential to reduce opioid use and improve pain control by targeting specific nerve pathways One of the more recent approaches is the quadratus lumborum block QLB which involves the injection of local anesthetics near the quadratus lumborum muscle This block is particularly useful in abdominal surgeries because it can provide pain relief by affecting both somatic and sympathetic nerves leading to broader and more effective pain coverage
The QLB has four different approaches anterior lateral posterior and intramuscular The anterior QLB is of particular interest in this setting because it involves the injection of local anesthetic between the quadratus lumborum and psoas muscles potentially allowing the anesthetic to spread into the thoracic paravertebral space This spread could result in the blockade of both the somatic nerves and the thoracic sympathetic chain offering more comprehensive pain relief that is beneficial for abdominal surgeries like colorectal procedures
The potential advantages of the anterior QLB in laparoscopic colorectal surgery include reduced postoperative pain decreased opioid consumption and fewer opioid-related side effects Additionally regional anesthesia techniques like QLB may reduce postoperative complications including respiratory issues which are particularly important in abdominal surgeries that involve the diaphragm and lower thoracic nerves
In this study the hypothesis is that bilateral subcostal anterior QLB administered during laparoscopic colorectal surgery will significantly reduce both postoperative pain and the need for opioids
The aim of this study is to investigate the effects of Bilateral subcostal anterior QLB on postoperative acute pain scores 0-24 hours and 24- hour opioid consumption in patients who underwent laparoscopic colorectal surgery Our study which the investigators think will contribute to the literature was planned as a prospective randomized controlled parallel-group study
Patients will be divided into two groups
Group S-QLB
A bilateral S-QLB 40 ml 025 bupivacaine 1400000 adrenaline will be performed In addition IV morphine-PCA will be applied postoperatively for 24 hours
Group Control
IV morphine-PCA will be applied postoperatively for 24 hours
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None