Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06647459
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-10-15
Brief Title:
Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial Fibrillation
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To use programmed ventricular stimulation at the time of AF ablation to define the prevalence and mechanism of inducible ventricular tachycardia VT pace-mapping to define the site of origin of ventricular arrhythmias and voltage mapping to define low voltage scar substrate in the basal LV in patients with pathogenic TTN variants compared to genotype-negative controls
Detailed Description:
Participants will undergo AF ablation according to standard contemporary techniques The procedure will be performed under general anesthesia As part of routine standard of care in patients with early-onset AF or patients who have PVCs we will also test for inducibility of VT using a standardized pacing protocol The research protocol will include LV mapping and identification of low voltage substrate using electroanatomical mapping as described below
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None