Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06646146
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-16
Brief Title:
Study on the Efficacy of Autologous Fat Grafting in Improving Hair Transplantation Outcomes for Patients With Localized Scleroderma-Related Alopecia
Sponsor:
None
Organization:
None
Study Overview
Official Title:
A Single-Center Prospective Randomized Controlled Clinical Study on the Efficacy of Autologous Fat Grafting in Improving Hair Transplantation Outcomes for Patients With Localized Scleroderma-Related Alopecia
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Investigating the efficacy and safety of autologous fat grafting combined with hair transplantation for the treatment of hair loss in patients with localized scleroderma
Detailed Description:
Localized scleroderma is an autoimmune disorder affecting the connective tissue with skin fibrosis being the primary symptom potentially leading to skin hardening atrophy and hair lossFor facial deformities associated with localized scleroderma current treatments primarily involve medication which can ameliorate disease activity but does not reverse the condition Hair transplantation can improve alopecia although the survival rate of hair follicles in patients with scleroderma may be lower than in the general population
Autologous fat grafting is a plastic surgery technique used for soft tissue augmentation and tissue regeneration The stem cells and growth factors present in adipose tissue contribute to hair regrowth Studies have indicated that autologous fat grafting when used adjunctively with hair transplantation can enhance the survival rate of hair follicles and increase patient satisfactionOur research team has developed a patented adipose matrix vascular component known as ECMSVF-gel This component is rich in active cells and holds potential for regenerative medicine It has been widely applied clinically to effectively ameliorate scar fibrosis and promote wound healing
Based on existing research we hypothesize that fat grafting may improve hair loss in patients with localized scleroderma and increase the survival rate of hair follicles We plan to conduct a randomized controlled study comparing hair transplantation assisted by ECMSVF-gel with traditional hair transplantation to validate our hypothesis and provide a more effective treatment option for patients with scleroderma
Autologous fat grafting is a plastic surgery technique used for soft tissue augmentation and tissue regeneration The stem cells and growth factors present in adipose tissue contribute to hair regrowth Studies have indicated that autologous fat grafting when used adjunctively with hair transplantation can enhance the survival rate of hair follicles and increase patient satisfactionOur research team has developed a patented adipose matrix vascular component known as ECMSVF-gel This component is rich in active cells and holds potential for regenerative medicine It has been widely applied clinically to effectively ameliorate scar fibrosis and promote wound healing
Based on existing research we hypothesize that fat grafting may improve hair loss in patients with localized scleroderma and increase the survival rate of hair follicles We plan to conduct a randomized controlled study comparing hair transplantation assisted by ECMSVF-gel with traditional hair transplantation to validate our hypothesis and provide a more effective treatment option for patients with scleroderma
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None