Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06643832
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-10-14
Brief Title:
Modulation of Propofol Injection Pain by Rubbing and Distraction
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Spinal and Supra-spinal Modulation of Propofol Injection Pain by Rubbing and Distraction A Randomized Controlled Study
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This prospective randomized controlled study will be conducted to evaluate the effects of rubbing and distraction on the incidence and severity of propofol injection pain and compare them with the standard intravenous lidocaine method
Detailed Description:
Propofol has become one of the most common anesthetic agents used for sedation induction and maintenance of anesthesia because of its unique pharmacological properties Pain during bolus injection is a major drawback with an incidence as high as 80-90 in an untreated patient
One of the most effective factors that alleviate the injection pain involves pretreatment with lidocaine
Spinal modulation of pain is explained by the melzack gate control theory it proposed that stimulation of A beta fibers by touch and vibration modulate the dorsal horn gate and therefore the nociceptive input from the periphery could be reduced 5 Regarding the use of this concept for managing propofol pain only one study was conducted and revealed that rubbing didnt decrease the incidence but significantly decreased the severity of pain
Distraction is a method of removing attention so it modifies cognitive pain perceptions by altering nociceptive responses and triggering an internal pain-suppressing system Therefore it causes a decrease in the activation of areas in the brain eg thalamus and insula which contribute significantly to pain perception we will combine rubbing and distraction as methods for spinal and supra-spinal pain modulation to evaluate their effects on propofol injection pain and compare them with the standard intravenous lidocaine method
One of the most effective factors that alleviate the injection pain involves pretreatment with lidocaine
Spinal modulation of pain is explained by the melzack gate control theory it proposed that stimulation of A beta fibers by touch and vibration modulate the dorsal horn gate and therefore the nociceptive input from the periphery could be reduced 5 Regarding the use of this concept for managing propofol pain only one study was conducted and revealed that rubbing didnt decrease the incidence but significantly decreased the severity of pain
Distraction is a method of removing attention so it modifies cognitive pain perceptions by altering nociceptive responses and triggering an internal pain-suppressing system Therefore it causes a decrease in the activation of areas in the brain eg thalamus and insula which contribute significantly to pain perception we will combine rubbing and distraction as methods for spinal and supra-spinal pain modulation to evaluate their effects on propofol injection pain and compare them with the standard intravenous lidocaine method
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None