Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06637956
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-10-07
Brief Title:
The Effect of Intranasally Administered Nitroglycerin on Hemodynamic Response to Laryngoscopy and Intubation Among Patients Undergoing Coronary Artery Bypass Grafting CABG Surgery
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effect of Intranasally Administered Nitroglycerin on Hemodynamic Response to Laryngoscopy and Intubation Among Patients Undergoing Coronary Artery Bypass Grafting CABG Surgery
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Numerous preventive medications have been used to lessen the cardiovascular response to laryngoscopy and intubation Though some advantages have been noted most of these treatments have not been found to be completely satisfying However nitroglycerin is the most widely utilized medicine due to its fast effect short half-life and absence of sedative qualities
Detailed Description:
The circulatory system under compromise is less resilient to the effects of general anaesthesia Inducing anaesthesia is a crucial step for cardiac patients because their impaired circulatory systems are less tolerant to depression During coronary artery bypass grafting surgery the primary objective of general anesthesia is to reduce sympathetic response to uncomfortable stimuli including laryngoscopy intubation skin incision sternal splitting and spreading A rise in blood pressure is one of the hemodynamic reactions that is typically associated with tracheal intubation and laryngoscopy The impact of intra nasally delivered nitroglycerin on blood pressure response to laryngoscopy and intubation in patients having non-cardiac surgery is currently contentious however this study focus on coronary artery bypass grafting surgery patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None