Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06636643
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-10-07
Brief Title:
The Effect of Bone Marrow Stem Cells Harvested from the Iliac Crest Versus Mandibular Ramus in Alveolar Cleft Regeneration
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effect of Bone Marrow Stem Cells Harvested from the Iliac Crest Versus Mandibular Ramus in Alveolar Cleft Regeneration
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This comparative and prospective study was conducted on 10 patients with alveolar cleft defects Patients with alveolar cleft defects were randomly selected and randomly divided into two equal groups Group A received Autologous BMMSCs harvested from the mandibular ramus and seeded on a collagen sponge in combination with nanohydroxyapatite Group B received Autologous BMMSCs harvested from the lilac crest and seeded on a collagen sponge in combination with nanohydroxyapatite
Detailed Description:
The utilization of Mandibular Ramus-derived BMSCs presents a groundbreaking advancement in maxillofacial reconstruction This approach offers numerous advantages including reduced surgical complications improved precision and localization higher osteogenic potential and lower risks of graft rejection Moreover the combination of BMMNCs nanohydroxyapatite and PRF extracted from the mandible proves to be a viable alternative to traditional iliac crest grafting promoting effective bone regeneration in alveolar cleft defects By adopting this novel technique and harvesting site It can can optimize surgical interventions paving the way for enhanced standards of care and improving the quality of life for patients with maxillofacial challenges
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None