Official Title: Impact of a 24-hour Shift Call on the Immune Status of Surgery Residents
Status: NOT_YET_RECRUITING
Status Verified Date: 2024-10
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Sleep deprivation is a prevalent problem in modern societies Sleep deprivation can cause hormonal changes such as an increase in cortisol as well as inflammation Animal studies have shown an increase in inflammatory cytokine production following sleep deprivation Additionally humans experiencing sleep deprivation may experience a decrease in natural killer cells and lymphocytes
Physicians particularly those in surgical specialties are often subjected to sleep deprivation as part of their medical residency training This study hypothesizes that after 24-hour shifts there is an increase in inflammatory response and impairment of the immune response against unspecific activation This proposal aims to provide insight into the impact of sleep deprivation on the immune system of surgery residents by characterizing the phenotype and function of immune cells as well as their correlation with biometric data