Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06629831
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-09-27
Brief Title:
Systemic Inflammatory Biomarkers in Ovarian Cancer
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effect of Preoperative Laboratory Values on Prognostic Factors Following Cytoreductive Surgery for Ovarian Cancer Neutrophil to Lymphocyte Ratio Platelet to Lymphocyte Ratio Lymphocyte to Monocyte Ratio
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In cancer patients prognostic markers are needed to improve the management and clinical course of both the cancer itself and surgery therefor Elevated systemic inflammatory markers are associated with morbidity and mortality in most cancer types In this study the investigators aimed to determine the prognostic value of inflammatory markers such as neutrophil to lymphocyte ratio NLR platelet to lymphocyte ratio PLR and lymphocyte to monocyte ratio LMR in patients undergoing cytoreductive surgery for ovarian cancer
Detailed Description:
Major gynaecological cancer surgery is a procedure with high complication rates and mortality risk due to both the patient s old age and comorbidities and the extent of the surgery Among such surgeries ovarian cancer-related surgery has the highest mortality rate Despite advances in early drug therapy and improvements in the cytotoxicity of drugs ovarian cancer is frequently diagnosed at advanced stages which further increases morbidity and mortality rates Although many years have passed the prognostic role of cytoreductive surgery on survival in ovarian cancers continues to be important Predicting postoperative outcomes in these surgeries may reduce the length of hospital stay need for stay in the intensive care unit complications and mortality Therefore the role of systemic inflammatory biomarkers needs to be comprehensively investigated to understand the carcinogenic mechanisms better
For this purpose the investigators planned to evaluate the prognostic effect of systemic inflammatory biomarkers on postoperative complications
For this purpose the investigators planned to evaluate the prognostic effect of systemic inflammatory biomarkers on postoperative complications
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None