Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06628596
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-10-03
Brief Title:
Acute Effects of Paraxanthine on Energy and Focus
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Acute Effects of Paraxanthine on Energy Focus Appetite and Cognition Double-Blind Placebo-Controlled Trial
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PXN
Brief Summary:
This study aims to evaluate the effects of paraxanthine 200 mg and 300 mg on energy focus appetite and cognitive performance in healthy adults Using a double-blind placebo-controlled crossover design participants will receive paraxanthine or placebo 30 minutes before a meal Cognition tests and visual Analogue Scale VAS ratings for energy focus productivity satiety and appetite will be collected at multiple time points post-consumption
Detailed Description:
Caffeine CAF is one of the most consumed naturally occurring nootropic and exercise-related ergogenic aids Paraxanthine 17-dimethylxanthine PXN is the main metabolite of CAF accounting for 70-72 of CAF ingested and 85 of the methylxanthine metabolic by-products While caffeine has been extensively studied for its effects on energy and focus in humans the effects of paraxanthine are less understood
It was recently reported that acute ingestion of PXN enhances various markers of focus such as memory reaction time and attention for up to 6-hours in healthy adults and that acute ingestion as low as 50 mg of PXN for 7-days enhanced measures of cognition memory reasoning response time and helped sustain attention While studies were performed in the fasted state and over 6 hours which is beyond the 31h half-life of paraxanthine the cognitive effects of paraxanthine in response to an ecologically valid meal over a 3-hour period is limited Therefore the purpose of this study is to assess the impact of paraxanthine on energy focus and cognition in younger healthy adults in the fed state
It was recently reported that acute ingestion of PXN enhances various markers of focus such as memory reaction time and attention for up to 6-hours in healthy adults and that acute ingestion as low as 50 mg of PXN for 7-days enhanced measures of cognition memory reasoning response time and helped sustain attention While studies were performed in the fasted state and over 6 hours which is beyond the 31h half-life of paraxanthine the cognitive effects of paraxanthine in response to an ecologically valid meal over a 3-hour period is limited Therefore the purpose of this study is to assess the impact of paraxanthine on energy focus and cognition in younger healthy adults in the fed state
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None