Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06627491
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-10-02
Brief Title:
Influence of Fast and Slow Imagined Muscle Contractions on Muscle Function or Central Nervous System Properties
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Does the Speed of Imagined Muscle Contractions Affect Muscle Function and Central Nervous System Excitability
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this randomized clinical trial is to learn if imagining fast or slow muscle contractions causes different responses for nervous system excitability and muscle function in young healthy males and females in The main questions are
Does imagining fast muscle contractions cause greater nervous system excitability compared to imagining slow muscle contractions
Does imagining fast muscle contractions increase muscle function compared to imagining slow muscle contractions
A control condition rest will be compared with two intervention conditions imagining fast and imagining slow conditions to determine if the fast and slow increase outcomes more than control and if fast has the greatest response
Participants will
Attend 4 laboratory visits
Perform 50 imagined contractions fast or slow but with no physical movement
Physical muscle contractions and non-invasive brain stimulation would be completed before and after each condition
Does imagining fast muscle contractions cause greater nervous system excitability compared to imagining slow muscle contractions
Does imagining fast muscle contractions increase muscle function compared to imagining slow muscle contractions
A control condition rest will be compared with two intervention conditions imagining fast and imagining slow conditions to determine if the fast and slow increase outcomes more than control and if fast has the greatest response
Participants will
Attend 4 laboratory visits
Perform 50 imagined contractions fast or slow but with no physical movement
Physical muscle contractions and non-invasive brain stimulation would be completed before and after each condition
Detailed Description:
Participants will complete 4 laboratory visits in a randomized order including a familiarization session a control condition and 2 conditions involving imaginary muscle contractions During visits involving imaginary muscle contractions participants will complete 2 sets of 25 repetitions of either fast ie less than 1 second to peak torque increase torque as fast as possible or slow ie 3 seconds to peak torque isometric elbow flexions Before and after each condition single-pulse transcranial magnetic stimulation will be delivered to the primary motor cortex to measure the amplitude of motor-evoked potentials and the duration of the resulting silent periods in the bicep brachii to quantify changes in corticospinal excitability and inhibition respectively Rapid maximal voluntary isometric contractions will be used to measure changes in rate of torque development peak torque and rate of muscle activation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None