Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06625554
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-27
Brief Title:
Urinary Tract Infection In Assiut University Children Hospital
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Antibiotic Sensitivity Pattern and Demographic Characteristics of Urinary Tract Infection In Assiut University Children Hospital
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Antibiotic Sensitivity Pattern and Demographic Characteristics of Urinary Tract Infection In Assiut University Children Hospital
Detailed Description:
Urinary tract infection is the third most common serious bacterial infection in childhood and has been identified as an important risk factor for the development of progressive renal impairment and longterm consequences
The epidemiology of UTI during childhood varies by age gender circumcision status and other factors Boys are more susceptible during the first year of life mostly in the first 3 months among boys uncircumcised infants have an eightfold higher risk due to phimosis limiteUrinary tract infection is the third most common serious bacterial infection in childhood and has been identified as an important risk factor for the development of progressive renal impairment and longterm consequences
The epidemiology of UTI during childhood varies by age gender circumcision status and other factors Boys are more susceptible during the first year of life mostly in the first 3 months among boys uncircumcised infants have an eightfold higher risk due to phimosis limited retraction of the foreskin is significantly associated with an increase in UTIs in male infants afterward the incidence is mainly higher in girls due to differences in anatomy About 5 of girls and 2 of boys experience at least one incident of UTI up to the age of 7 years
Symptoms of UTI may be minimal and non-specific in infants and small children Febrile children not suspected of having UTI are as likely to have UTI as those who are suspected of having UTI Therefore diagnosis of UTI can not be made on symptomatology alone and urine examination is advocated in children with minimal suspicion of UTI
Etiological agents of UTI are variable and usually depend on time geographical location and age of patients However Escherichia coli Proteus mirabilis Enterobacter agglomerans Citrobacter frreundii and Klebsiella pneumonia account for over 70 of cases
According to sex and age the incidence and clinical symptoms vary and the causative organisms are different in pediatric UTI In addition as antibiotic-resistant pathogens change and are increased due to the abuse of antibiotics and inappropriate selection it is necessary to select proper antibiotics in the early phase of treatment Thus regular antibiotic sensitivity results from the evaluation of UTI are important to improve the effectiveness of treatment
The gold standard for the diagnosis of UTI is the detection of the pathogen in urine The pathogen is detected and identified in urine which contributes to antibacterial treatment Rapid administrations of empirical antibiotics are required before urine culture testing Meanwhile complicated UTI often increase the prevalence of inappropriate antibacterial treatment which in turn increases antibiotic resistance ABR In pediatric UTI ABR is also being raised as a clinical challenge Therefore there is an urgent need to identify which bacterial strains in children and explore their susceptibility to commonly used antimicrobials It could guide effective antibacterial therapy and reduce the multi-drug resistance prevalence in children
In our study we will collect the age sex clinical characteristics for children microorganism isolation and antimicrobial susceptibility profile in children who had been diagnosed with UTI
According to sex and age the incidence and clinical symptoms vary and the causative organisms are different in pediatric UTI In addition as antibiotic-resistant pathogens change and are increased due to the abuse of antibiotics and inappropriate selection it is necessary to select proper antibiotics in the early phase of treatment Thus regular antibiotic sensitivity results from the evaluation of UTI are important to improve the effectiveness of treatment
The gold standard for the diagnosis of UTI is the detection of the pathogen in urine The pathogen is detected and identified in urine which contributes to antibacterial treatment Rapid administrations of empirical antibiotics are required before urine culture testing Meanwhile complicated UTI often increase the prevalence of inappropriate antibacterial treatment which in turn increases antibiotic resistance ABR In pediatric UTI ABR is also being raised as a clinical challenge Therefore there is an urgent need to identify which bacterial strains in children and explore their susceptibility to commonly used antimicrobials It could guide effective antibacterial therapy and reduce the multi-drug resistance prevalence in children
In our study we will collect the age sex clinical characteristics for children microorganism isolation and antimicrobial susceptibility profile in children who had been diagnosed with UTI
The epidemiology of UTI during childhood varies by age gender circumcision status and other factors Boys are more susceptible during the first year of life mostly in the first 3 months among boys uncircumcised infants have an eightfold higher risk due to phimosis limiteUrinary tract infection is the third most common serious bacterial infection in childhood and has been identified as an important risk factor for the development of progressive renal impairment and longterm consequences
The epidemiology of UTI during childhood varies by age gender circumcision status and other factors Boys are more susceptible during the first year of life mostly in the first 3 months among boys uncircumcised infants have an eightfold higher risk due to phimosis limited retraction of the foreskin is significantly associated with an increase in UTIs in male infants afterward the incidence is mainly higher in girls due to differences in anatomy About 5 of girls and 2 of boys experience at least one incident of UTI up to the age of 7 years
Symptoms of UTI may be minimal and non-specific in infants and small children Febrile children not suspected of having UTI are as likely to have UTI as those who are suspected of having UTI Therefore diagnosis of UTI can not be made on symptomatology alone and urine examination is advocated in children with minimal suspicion of UTI
Etiological agents of UTI are variable and usually depend on time geographical location and age of patients However Escherichia coli Proteus mirabilis Enterobacter agglomerans Citrobacter frreundii and Klebsiella pneumonia account for over 70 of cases
According to sex and age the incidence and clinical symptoms vary and the causative organisms are different in pediatric UTI In addition as antibiotic-resistant pathogens change and are increased due to the abuse of antibiotics and inappropriate selection it is necessary to select proper antibiotics in the early phase of treatment Thus regular antibiotic sensitivity results from the evaluation of UTI are important to improve the effectiveness of treatment
The gold standard for the diagnosis of UTI is the detection of the pathogen in urine The pathogen is detected and identified in urine which contributes to antibacterial treatment Rapid administrations of empirical antibiotics are required before urine culture testing Meanwhile complicated UTI often increase the prevalence of inappropriate antibacterial treatment which in turn increases antibiotic resistance ABR In pediatric UTI ABR is also being raised as a clinical challenge Therefore there is an urgent need to identify which bacterial strains in children and explore their susceptibility to commonly used antimicrobials It could guide effective antibacterial therapy and reduce the multi-drug resistance prevalence in children
In our study we will collect the age sex clinical characteristics for children microorganism isolation and antimicrobial susceptibility profile in children who had been diagnosed with UTI
According to sex and age the incidence and clinical symptoms vary and the causative organisms are different in pediatric UTI In addition as antibiotic-resistant pathogens change and are increased due to the abuse of antibiotics and inappropriate selection it is necessary to select proper antibiotics in the early phase of treatment Thus regular antibiotic sensitivity results from the evaluation of UTI are important to improve the effectiveness of treatment
The gold standard for the diagnosis of UTI is the detection of the pathogen in urine The pathogen is detected and identified in urine which contributes to antibacterial treatment Rapid administrations of empirical antibiotics are required before urine culture testing Meanwhile complicated UTI often increase the prevalence of inappropriate antibacterial treatment which in turn increases antibiotic resistance ABR In pediatric UTI ABR is also being raised as a clinical challenge Therefore there is an urgent need to identify which bacterial strains in children and explore their susceptibility to commonly used antimicrobials It could guide effective antibacterial therapy and reduce the multi-drug resistance prevalence in children
In our study we will collect the age sex clinical characteristics for children microorganism isolation and antimicrobial susceptibility profile in children who had been diagnosed with UTI
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None