Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06622343
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-09-29
Brief Title:
Predictive Modeling of Necrotizing Skin Infections in Snakebite Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Risk Factor Analysis and Predictive Modeling for Necrotizing Skin Infections in Venomous Snakebite Patients A Multicenter Retrospective Study
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This multicenter retrospective study aims to identify the risk factors associated with necrotizing skin infections following venomous snakebites and to develop a predictive model Clinical data from 99 patients treated between January 2020 and April 2024 at three hospitals in Guangdong Province China were analyzed
Detailed Description:
Venomous snakebites are a significant public health issue particularly in tropical and subtropical regions like southern China Necrotizing skin infections are a severe but relatively rare complication of venomous snakebites often resulting from delayed treatment and bacterial invasion This study retrospectively analyzed clinical data from 99 patients with venomous snakebites treated at three hospitals in Guangdong Province between January 2020 and April 2024 The primary objective was to identify the major risk factors associated with the development of necrotizing skin infections and to build a predictive model to assist in clinical decision-making
The study included male and female patients aged 14 years and older Patients with incomplete medical records long-term use of immunosuppressants or underlying immunodeficiency diseases were excluded Multivariate logistic regression identified the Snakebite Severity Score SSS blood glucose levels and D-dimer levels as significant independent predictors of necrotizing infections
The study included male and female patients aged 14 years and older Patients with incomplete medical records long-term use of immunosuppressants or underlying immunodeficiency diseases were excluded Multivariate logistic regression identified the Snakebite Severity Score SSS blood glucose levels and D-dimer levels as significant independent predictors of necrotizing infections
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None