Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06621186
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-29
Brief Title:
Construction of an in Vitro Intestinal Microbial Ecological Simulation System for Obese People
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Construction of an in Vitro Intestinal Microbial Ecological Simulation System for Obese People
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
About 26 billion people about 40 of the world s population are affected by overweight or obesity The prevalence of overweight and obesity in Chinese adults has exceeded 50 and the prevalence is still on the riseThe gut microbiota is regarded as an endocrine organ and participates in energy balance Diet changes can disrupt the relationship between the microbiota and the host leading to metabolic diseasesAlthough human studies provide important information there are limitations such as the entry of complex gastrointestinal environment limiting components the lack of dynamic microbial process information and the uncertainty of drug side effects In vitro methods can solve these problems allowing dynamic sampling standardized operation high repeatability and evaluation of potential toxins and pathogens In vitro models are widely used to evaluate the effects on the human colon microbiome and to predict in vivo resultsBased on the above research background this study aims to collect fecal samples from obese people to construct an in vitro intestinal microbial ecological simulation system This will lay an experimental foundation for further exploring the effect of specific nutrient intervention on the composition and function of gut microbiota in obese people
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None