Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06620068
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-24
Brief Title:
Causal Relationship Between Plasma VEGF Family Proteins and Placenta Previa A Two-Sample Mendelian Randomization Study
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Causal Association Between Plasma Vascular Endothelial Growth Factor Family Proteins and Placenta Previa A Two-Sample Mendelian Randomization Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
VEGF PP
Brief Summary:
This study aims to investigate the causal relationship between plasma vascular endothelial growth factor VEGF family proteins and placenta previa using a two-sample Mendelian randomization MR approach Genome-wide association study GWAS data will be analyzed to assess the correlation and potential causality between VEGF protein levels and the occurrence of placenta previa
Detailed Description:
Placenta previa is a serious complication during pregnancy leading to significant risks for both the mother and the fetus This study utilizes Mendelian randomization MR to explore the potential causal link between plasma levels of VEGF family proteins including VEGFA VEGFB VEGFC VEGFD and PLGF and the risk of placenta previa By using genome-wide association study GWAS data from the UK Biobank and FinnGen datasets the study aims to provide insights into the role of angiogenesis and abnormal placental development The MR analysis will help minimize confounding factors and provide robust evidence regarding the causal relationship between VEGF proteins and placenta previa
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None