Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06618352
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-23
Brief Title:
Physiological Strain in Young Adults During a Simulated Heat Wave
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effects of Indoor Overheating on Physiological Strain in Young Adults During a Simulated Multi-day Heat Event
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The likelihood of exposure to overheated indoor environments is increasing as climate change is exacerbating the frequency and severity of hot weather and extreme heat events Prolonged exposure to excessive heat stress can result in a deterioration in physiological function leading to a myriad of pathophysiological conditions eg heat exhaustion acute kidney injury adverse cardiovascular events heat stroke that if left untreated can lead to death While the relationship between extreme heat events and human health has been assessed in relation to outdoor exposure to high heat conditions relatively little is known about the effects of daylong exposures to indoor overheating on the bodys physiology
In this study investigators will examine the change in physiological responses ie thermal cardiovascular in young 18-35 years adults exposed to successive days and nights of high indoor temperatures typical of conditions recording in dwellings without air conditioning during the 2021 Western Heat Dome Specifically study participants will be housed in a large environmental chamber outfitted with bed work space sitting area kitchen and bathroom for three successive days three days and two nights while exposed to indoor overheating where daytime temperatures will be maintained at 36C 45 relative humidity note 36C temperatures experienced in homes without air-conditioning for a 10-hour daytime exposure period DAYTIME defined as the time period from 900 to 1900 For the nighttime exposure period NIGHTTIME defined as the time period from 1900 to 900 participants will be exposed to nighttime temperatures fixed at 31C 45 relative humidity note reductions in indoor temperatures during the nighttime in large urban centers range between 4-6C Participants will be permitted to move freely throughout the day in the chamber but will be restricted from performing any physical activity except for the completion of a battery of tests cardiovascular cognitive and posture assessments performed prior to as performed between 700 and 900 and the end as performed between 1700 and 1900 of the daytime exposure During the nighttime period participants will be permitted to move freely until they decide to go to bed
In this study investigators will examine the change in physiological responses ie thermal cardiovascular in young 18-35 years adults exposed to successive days and nights of high indoor temperatures typical of conditions recording in dwellings without air conditioning during the 2021 Western Heat Dome Specifically study participants will be housed in a large environmental chamber outfitted with bed work space sitting area kitchen and bathroom for three successive days three days and two nights while exposed to indoor overheating where daytime temperatures will be maintained at 36C 45 relative humidity note 36C temperatures experienced in homes without air-conditioning for a 10-hour daytime exposure period DAYTIME defined as the time period from 900 to 1900 For the nighttime exposure period NIGHTTIME defined as the time period from 1900 to 900 participants will be exposed to nighttime temperatures fixed at 31C 45 relative humidity note reductions in indoor temperatures during the nighttime in large urban centers range between 4-6C Participants will be permitted to move freely throughout the day in the chamber but will be restricted from performing any physical activity except for the completion of a battery of tests cardiovascular cognitive and posture assessments performed prior to as performed between 700 and 900 and the end as performed between 1700 and 1900 of the daytime exposure During the nighttime period participants will be permitted to move freely until they decide to go to bed
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None