Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06618209
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-09-04
Brief Title:
Assessment of Oral Health Status of Children With Primary Ciliary Dyskinesia
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Assessment of Oral Health Status of Children With Primary Ciliary Dyskinesia
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to compare the oral health findings salivary parameters and pediatric oral health related quality of life of children with Primary Ciliary Dyskinesia PCD with healthy children
Detailed Description:
Primary Ciliary Dyskinesia PCD is a rare genetic disorder that affects the function of cilia which are tiny hair-like structures responsible for moving mucus and other substances in the respiratory tract and other parts of the body Dysfunctional cilia lead to impaired mucociliary clearance resulting in chronic respiratory infections sinusitis and bronchiectasis PCD can also cause situs inversus where internal organs are mirrored from their normal positions and other complications like chronic otitis media and fertility issues Early diagnosis and management are crucial to prevent progressive lung damage and improve the quality of life in affected individuals
This study aims to compare the oral and dental health of children diagnosed with Primary Ciliary Dyskinesia PCD to that of healthy controls The study includes assessments of dental caries using DMFT dmft and ICDAS II indices salivary parameters flow rate pH buffering capacity oxidant-antioxidant levels tissue factor activity enamel defects using the Modified Developmental Defects of Enamel Index and oral hygiene gingival and plaque indices The Pediatric Oral Health-Related Quality of Life POQL scale will be used to evaluate the impact of oral health on quality of life
This study aims to compare the oral and dental health of children diagnosed with Primary Ciliary Dyskinesia PCD to that of healthy controls The study includes assessments of dental caries using DMFT dmft and ICDAS II indices salivary parameters flow rate pH buffering capacity oxidant-antioxidant levels tissue factor activity enamel defects using the Modified Developmental Defects of Enamel Index and oral hygiene gingival and plaque indices The Pediatric Oral Health-Related Quality of Life POQL scale will be used to evaluate the impact of oral health on quality of life
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None