Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06613776
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-09-20
Brief Title:
Evaluation of the Effect of Antibiotic Prophylaxis 2g Amoxicillin One Hour Before Surgery on an Inflammatory Factor PGE2 in Salivary Samples After Third Molars Surgery
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Evaluation of the Effect of Antibiotic Prophylaxis on Inflammatory Factor in Salivary Samples After Third Molars Surgery
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This clinical trial aims to evaluate the impact of antibiotics on inflammation and pain in patients who have undergone mandibular third molar surgery The primary research questions are
1 Do antibiotics reduce pain following third molar surgery
2 Do antibiotics influence facial swelling and the patient39s ability to open their mouth
3 Do antibiotics affect the levels of a specific inflammatory marker in saliva post-surgery
Participants will be randomly assigned to receive either antibiotic capsules or placebo capsules The study will include the following procedures
Medication Participants will take four capsules either antibiotics or placebo as part of their standard surgical care
Saliva Samples Saliva samples will be collected at three time points before surgery 24 hours after surgery and 7 days post-surgery
Measurements Facial swelling and mouth opening will be assessed by the investigator at each time point
By comparing the outcomes between the antibiotic and placebo groups researchers aim to determine the effectiveness of antibiotics in managing post-surgical inflammation and pain
1 Do antibiotics reduce pain following third molar surgery
2 Do antibiotics influence facial swelling and the patient39s ability to open their mouth
3 Do antibiotics affect the levels of a specific inflammatory marker in saliva post-surgery
Participants will be randomly assigned to receive either antibiotic capsules or placebo capsules The study will include the following procedures
Medication Participants will take four capsules either antibiotics or placebo as part of their standard surgical care
Saliva Samples Saliva samples will be collected at three time points before surgery 24 hours after surgery and 7 days post-surgery
Measurements Facial swelling and mouth opening will be assessed by the investigator at each time point
By comparing the outcomes between the antibiotic and placebo groups researchers aim to determine the effectiveness of antibiotics in managing post-surgical inflammation and pain
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None