Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06613555
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-23
Brief Title:
Retinal Microvascularization in OCT-angiography and Systemic Diseases
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Retinal Microvascularization in OCT-angiography and Systemic Diseases
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OCTAVA
Brief Summary:
Systemic diseases are inflammatory chronic illnesses affecting different organs and altering their function At present there are few non-invasive methods for predicting their onset and progression
Some chronic diseases can be anticipated earlier thanks to predictive indicators These indicators could help doctors decide which treatment is best suited to each patient In particular the state of microcirculation in the eyes specifically in the retina is linked to the progression of certain diseases in the body Unfortunately assessing the health of the small blood vessels in the retina is complicated Most current methods are imprecise difficult to reproduce and require qualified specialists However the use of retinal microcirculation appears to be a promising approach to solving these problems
In fact the structure of retinal blood vessels can be observed easily painlessly and without invasive procedures thanks to fundus photographs or scans providing imaging slices known as optical coherence tomography-angiography OCT-A
The vascularization of the retina is very often presented as a window giving access to the peripheral vascularization the vascularization of other organs distant from the eyes
For example we recently demonstrated a link between retinal vascularization and the risk of heart problems in patients with coronary artery disease
The aim of this study is to gather original information on the evolution of retinal vascularization using specific markers that may be associated with damage to distant organs
By regularly monitoring these changes over time the researchers hope to identify early changes that could indicate the development or evolution of these diseases
The main aim of this study is to create a database of images obtained by OCT-Angiography in patients with systemic diseases and in healthy individuals This will enable us to identify early changes in retinal vascularization that may be associated with these systemic pathologies
With this information we hope to improve early diagnosis and monitoring of diseases which could have a positive impact on patients39 health
Some chronic diseases can be anticipated earlier thanks to predictive indicators These indicators could help doctors decide which treatment is best suited to each patient In particular the state of microcirculation in the eyes specifically in the retina is linked to the progression of certain diseases in the body Unfortunately assessing the health of the small blood vessels in the retina is complicated Most current methods are imprecise difficult to reproduce and require qualified specialists However the use of retinal microcirculation appears to be a promising approach to solving these problems
In fact the structure of retinal blood vessels can be observed easily painlessly and without invasive procedures thanks to fundus photographs or scans providing imaging slices known as optical coherence tomography-angiography OCT-A
The vascularization of the retina is very often presented as a window giving access to the peripheral vascularization the vascularization of other organs distant from the eyes
For example we recently demonstrated a link between retinal vascularization and the risk of heart problems in patients with coronary artery disease
The aim of this study is to gather original information on the evolution of retinal vascularization using specific markers that may be associated with damage to distant organs
By regularly monitoring these changes over time the researchers hope to identify early changes that could indicate the development or evolution of these diseases
The main aim of this study is to create a database of images obtained by OCT-Angiography in patients with systemic diseases and in healthy individuals This will enable us to identify early changes in retinal vascularization that may be associated with these systemic pathologies
With this information we hope to improve early diagnosis and monitoring of diseases which could have a positive impact on patients39 health
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None