Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06613542
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-17
Brief Title:
Effects of Daily Taurine Intake for 6 Months on Biological Age and Body Metabolism Indicators As Well As Physical Fitness in 55-75-year-old Women and Men
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effect of Daily Taurine Supplementation for 6 Months on Biological Age and Metabolic Biomarkers As Well As Physical Fitness in 55-75-year-old Women and Men a Randomized Controlled Intervention Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TauAge
Brief Summary:
The goal of this clinical trial is to investigate the effect of taking 4 grams of taurine by older adults on aging processes over a period of 6 months It will also check for effects of taurine on participants physical fitness metabolic and cognitive functions The main question it aims to answer is
Does a supplementation with 4 g of taurine daily over a period of 6 months slow down biological aging in humans Researchers will compare supplementation with taurine to a placebo a look-alike substance that contains no drug to reliably determine whether taurine has an effect
Participants will
Take 4g of taurine or a placebo every day for 6 months
Visit the study site 4 times for checkups and tests for a screening visit at the beginning of the intervention after 8 and 24 weeks
Does a supplementation with 4 g of taurine daily over a period of 6 months slow down biological aging in humans Researchers will compare supplementation with taurine to a placebo a look-alike substance that contains no drug to reliably determine whether taurine has an effect
Participants will
Take 4g of taurine or a placebo every day for 6 months
Visit the study site 4 times for checkups and tests for a screening visit at the beginning of the intervention after 8 and 24 weeks
Detailed Description:
Measurements performed during study visits
Biological age estimate via proteome analysis
Organ age estimates proteomics
DNA methylation
Inflammatory biomarkers CRP cytokines
Metabolic variables fasting blood glucose insulin HOMA-IR HbA1c lipids BMI
Physical fitness hand grip strength leg extensor strength PWC130
Resting energy expenditure
Cognitive function via questionnaire
Quality of life
Heart rate variability
Physical activity nutrition
Biological age estimate via proteome analysis
Organ age estimates proteomics
DNA methylation
Inflammatory biomarkers CRP cytokines
Metabolic variables fasting blood glucose insulin HOMA-IR HbA1c lipids BMI
Physical fitness hand grip strength leg extensor strength PWC130
Resting energy expenditure
Cognitive function via questionnaire
Quality of life
Heart rate variability
Physical activity nutrition
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None