Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06612372
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-19
Brief Title:
Effects of 60-day-6 Head-down Bed Rest on Cartilage and Function of the Knee Joint
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effects of 60-day-6 Head-down Bed Rest on Cartilage and Function of the Knee Joint
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objective To investigate the effects of long-term simulated unloading in bed on articular cartilage quality based on functional magnetic resonance imaging FMRI and Knee joint function
Detailed Description:
A total of 26 subjects were recruited for a 60-day period of head-down bed rest HDBR The bed rest position is a 6 downward tilt of the head and all daily activities are performed in this position We will perform functional MRI scans of the right knee joint using T2 mapping sequences to assess tissue composition and water content before and after HDBR Functional assessments including the Y-Balance Test and International Knee Documentation Committee IKDC scores were performed pre-HDBR and post-HDBRWe will divide each participants knee cartilage into 18 regions and measured T2 values according to the whole organ magnetic resonance imaging score WORMS partitioning method
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None