Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06609356
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-20
Brief Title:
Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ACT T1D
Brief Summary:
This study aims to understand the heart and blood sugar health benefits of using an adjunctive therapy to lower high insulin levels in people with type 1 diabetes The investigators will also look at people with a specific type of diabetes called Glucokinase-Maturity Onset Diabetes of the Young GCK-MODY and those without diabetes to help interpret the results The investigators will use a medication that helps the body get rid of sugar called and SGLT2 inhibitor with the goal to reduce the bodyamp39s insulin requirements The investigators believe this could lead to better heart and blood sugar health including a better response to insulin and more available nitric oxide a gas that helps blood vessels function well The investigators will compare heart and blood sugar health risk factors in participants with type 1 diabetes participants with Glucokinase-Maturity Onset Diabetes of the Young GCK-MODY and non-diabetic healthy volunteers under two conditions high insulin levels typical of type 1 diabetes and normal insulin levels typical of the other two groups
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None