Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06602050
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-04
Brief Title:
Maximum Inspiratory Pressure Grip Strength and Physical Functional Status Relationship in MV Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Determination of the Relationship Between Maximum Inspiratory Pressure Grip Strength and Physical Functional Status in Mechanically Ventilated Patients
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The maximal inspiratory pressure or negative inspiratory force values is a parameter that measures the functional ability of the respiratory system The ability to reduce the risk of atelectasis effective coughing and mobilization of airway secretions is directly proportional to the magnitude of this value Grip strength is a parameter that noninvasively assesses functional status in critical care patientsRespiratory muscles work in a complex interaction with peripheral muscles This dynamic relationship has been described in many populationsThe aim of this study was to determine the relationship between maximum inspiratory pressure and grip strength and physical functional status in mechanical ventilator patients
Detailed Description:
Progressive inadequate ventilation results in multiple organ dysfunction due to impaired oxygenation and subsequent hypoxia Additionally the combined effects of reduced exercise capacity and increased oxidative stress contribute to cardiovascular failure further immobilization increased peripheral muscle weakness and a diminished quality of life From this standpoint there is a dynamic interaction between the respiratory muscles and peripheral striated muscles strengthening one muscle group positively influences the other Respiratory muscle strength is closely related to both limb muscle strength and endurance Therefore it is essential to assess not only respiratory but also peripheral muscle strength in mechanically ventilated patients
Maximum Inspiratory Pressure MIP and Maximum Expiratory Pressure MEP are functional units used to assess respiratory muscle strength In this context various measurement methods developed to determine MIP and MEP provide valuable insights into the condition of patients39 respiratory muscles Although invasive methods are sometimes used to evaluate respiratory muscle strength in mechanically ventilated patients simple bedside measurements are often sufficient One such method particularly for ventilator-dependent patients utilizes the negative inspiratory pressure value available through the ventilator39s software features In this procedure the intensive care unit clinician instructs the patient to perform a strong inspiratory effort against a 34closed circuit34 within the system and the resulting pressure serves as an indicator of inspiratory muscle strength It is crucial that the patient is informed about the absence of airflow during this procedure and that they are cooperative
Peripheral muscle strength is typically assessed using muscle strength tests or isokinetic evaluations Additionally grip strength measurement serves as a non-invasive indicator of both functional status and peripheral muscle strength in patients on mechanical ventilation Respiratory muscles work in a complex interaction with peripheral musclesThis dynamic relationship has been described in many populations In certain disease groups peripheral muscle strength has been assessed through grip strength while respiratory muscle strength was measured using maximal inspiratory pressure MIP and maximal expiratory pressure MEP values allowing for the determination of the relationship between these two muscle groups Typically MIP is measured in the literature using manometers and specialized devices However this study was designed to measure MIP using the negative inspiratory pressure value-equivalent to maximal inspiratory pressure-directly from the mechanical ventilation device without the use of external equipment and without disconnecting the patient from the respiratory circuitThe aim of this study is to determine the relationship between maximal inspiratory pressure grip strength and physical functional status in mechanically ventilated patients
Maximum Inspiratory Pressure MIP and Maximum Expiratory Pressure MEP are functional units used to assess respiratory muscle strength In this context various measurement methods developed to determine MIP and MEP provide valuable insights into the condition of patients39 respiratory muscles Although invasive methods are sometimes used to evaluate respiratory muscle strength in mechanically ventilated patients simple bedside measurements are often sufficient One such method particularly for ventilator-dependent patients utilizes the negative inspiratory pressure value available through the ventilator39s software features In this procedure the intensive care unit clinician instructs the patient to perform a strong inspiratory effort against a 34closed circuit34 within the system and the resulting pressure serves as an indicator of inspiratory muscle strength It is crucial that the patient is informed about the absence of airflow during this procedure and that they are cooperative
Peripheral muscle strength is typically assessed using muscle strength tests or isokinetic evaluations Additionally grip strength measurement serves as a non-invasive indicator of both functional status and peripheral muscle strength in patients on mechanical ventilation Respiratory muscles work in a complex interaction with peripheral musclesThis dynamic relationship has been described in many populations In certain disease groups peripheral muscle strength has been assessed through grip strength while respiratory muscle strength was measured using maximal inspiratory pressure MIP and maximal expiratory pressure MEP values allowing for the determination of the relationship between these two muscle groups Typically MIP is measured in the literature using manometers and specialized devices However this study was designed to measure MIP using the negative inspiratory pressure value-equivalent to maximal inspiratory pressure-directly from the mechanical ventilation device without the use of external equipment and without disconnecting the patient from the respiratory circuitThe aim of this study is to determine the relationship between maximal inspiratory pressure grip strength and physical functional status in mechanically ventilated patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None