Viewing Study NCT06601738



Ignite Creation Date: 2024-10-26 @ 3:40 PM
Last Modification Date: 2024-10-26 @ 3:40 PM
Study NCT ID: NCT06601738
Status: RECRUITING
Last Update Posted: None
First Post: 2024-09-16

Brief Title: Isometric and Dynamic Handgrip Training Effects on Hypertension
Sponsor: None
Organization: None

Study Overview

Official Title: Effects Of Isometrics and Dynamic Handgrip Exercise Training On Cardiovascular Parameters In Hypertensive Patients
Status: RECRUITING
Status Verified Date: 2024-09
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Essential hypertension accounts for 13 percent of total deaths worldwide accounting for one of the major risk factors Hypertension high blood pressure is when the pressure in your blood vessels is too high 14090 mmHg or higher Dynamic exercises sustained hand grip contractions elicit lower systolic blood pressure and heart rate responses So for patients undergoing exercise therapy low intensity isometric exercises are preferable Significant reduction is seen in mean arterial blood pressure and systolic blood pressure in individuals conducting isometric for 8 weeks in 30 The reduction in systolic blood pressure will be clinically significant The main objective of this study will be to determine the effects of dynamic and isometric handgrip exercise training on cardiovascular parameters in hypertensive patients Grade 1 hypertensive patients are included as per AHA and JNC7 criteria A sample of 100 hypertensive patients will be recruited and divided into two treatment groups G1 dynamic exercise in hypertensive patients and G2 isometric exercise in hypertensive patients Outcome measure will include systolic blood pressure diastolic blood pressure mean arterial blood pressure and pulse pressure Outcome measures will be assessed at baseline and 2nd and 4th weeks posttreatment
Detailed Description: Hypertension is one of the most prevalent diseases leading to morbidity and mortality affecting millions of people every year Pharmaceutical management is the main treatment method used Exercise therapy mainly isometrics and dynamic handgrip exercises provide a non pharmacological management leading to decrease in symptoms The association of hypertension with physical inactivity sedentary behavior and occupational exposure to chemicals obesity older age genetics being overweight or obese not being physically active high-salt diet job insecurity job loss and the psychosocial work environment and drinking too much alcohol Lifestyle changes like eating a healthier diet quitting tobacco and being more active can help lower blood pressure Hypertension rates are strongly associated with age Acute effects of isometric and dynamic handgrip exercise on cardiovascular parameters in hypertensive subjects are numerous They may also have some adverse effects on the cardiorespiratory system particularly through the elevation of blood pressure

Since an acute bout of exercise can transiently improve cardiovascular endothelial function arterial stiffness and ambulatory blood pressure The dynamic handgrip exercise is performed by repetitive contraction and relaxation of the hand at a maximum frequency In order to determine the intensity of handgrip exercises maximum isometric handgrip strength of the right and left hand was measured with a handgrip dynamometer Isometric exercises differ from dynamic exercises because in this there is no change in muscle length or static force Single handgrip exercise could reduce the blood pressure for couple of hours so a patient can perform this exercise several times a day if not being fatigue

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None