Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06601608
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-15
Brief Title:
Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Efficacy of Locally Delivered Rosemary Extract Gel As an Adjunct to Non-Surgical Periodontal Therapy in Management of Periodontitis A Randomized Controlled Clinical Trial with Microbiological Analysis
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Rosemary extract is known for its antibacterial anti-inflammatory and anti-oxidant properties that make it a promising therapeutic aid as a local delivery drug in deep periodontal pockets in adjunct to non-surgical periodontal therapy in management of periodontitis These properties are due to the high content of phenolic compounds such as carnosic acid urolic acid rosmarinic acid or chlorogenic acid Rosemary extract was previously investigated and proved its effectiveness against periodontopathogens in-vitro Thus its selected for this study to be administered in a gel form to assess its efficacy in management of periodontitis
Detailed Description:
Sixteen patients with deep periodontal pockets more than 5 mm will be randomly assigned into 2 equal groups The test group will receive the rosemary extract gel in adjunct to non-surgical periodontal therapy while the control group will receive placebo gel
Clinical evaluation of the clinical parameters including probing depth gingival index plaque index and clinical attachment level will be recorded
Microbiological analysis using PCR test will be performed using perio-papers
Clinical evaluation of the clinical parameters including probing depth gingival index plaque index and clinical attachment level will be recorded
Microbiological analysis using PCR test will be performed using perio-papers
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None