Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06601374
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-11
Brief Title:
Patient Presented With AKI Related to Pregnancy
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Characteristics and Outcomes of Patients With Pregnancy Related Acute Kidney Injury in Assiut University Hospitals a Single-center Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary objective of this study is to identify characteristics of patient with PR AKI treated in Assiut university hospital
Secondary outcomes
1 Assessment of pregnancy related AKI maternal outcome complete recovery partial recovery or progress to ESRD within 3 months duration
2 To identify predictors of unfavorable outcome of patient with pregnancy related AKI
Secondary outcomes
1 Assessment of pregnancy related AKI maternal outcome complete recovery partial recovery or progress to ESRD within 3 months duration
2 To identify predictors of unfavorable outcome of patient with pregnancy related AKI
Detailed Description:
Acute kidney Injury AKI is a syndrome which is characterized by an rapid deterioration of the kidney function manifested by increase in serum creatinine level with or without reduced urine output and linked to high rate of morbidity and mortality AKI is considered a major public health problem despite much improvmnent in heakth care and especially most of them about 85 in developing countries with low resourcesPregnancy related AKI PR -AKI is a major obstetric complication which may cause termination of pregnancy TOP Intensive care unit ICU admission need for dialysiy both maternal and perinatal morbidity and mortality with maternal mortality rang from 9 to 55
PR-AKI has a major risk factors include preeclampsia which is the most common cause 15-20 hyperemesis gravidarum acute fatty liver of pregnancy and placental abruption puerperal sepsis and septic abortion The maternal outcome of pregnancy related AKI include complete recovery with return of serum creatinine to normal gt 14 mg dl about 40-75 partial recovery4-9 require dialysis about 4 months after delivery progress to End stage renal disease 15 - 25 or maternal mortality The maternal mortality rate MMR increases with increasing severity of pregnancy-related complications and can range from 13 to 24 in developing countries due to PR-AKI
Timely identification of patients and management of underlying conditions is considered the cornerstone to improve maternal outcome
PR-AKI has a major risk factors include preeclampsia which is the most common cause 15-20 hyperemesis gravidarum acute fatty liver of pregnancy and placental abruption puerperal sepsis and septic abortion The maternal outcome of pregnancy related AKI include complete recovery with return of serum creatinine to normal gt 14 mg dl about 40-75 partial recovery4-9 require dialysis about 4 months after delivery progress to End stage renal disease 15 - 25 or maternal mortality The maternal mortality rate MMR increases with increasing severity of pregnancy-related complications and can range from 13 to 24 in developing countries due to PR-AKI
Timely identification of patients and management of underlying conditions is considered the cornerstone to improve maternal outcome
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None