Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06597630
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-02
Brief Title:
Pathological TypeGene Mutation and Clinical Characteristics of Unilateral Primary Aldosteronism
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Pathological TypeGene Mutation and Clinical Characteristics of Unilateral Primary AldosteronismA Prospective Study
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
1 Aim to investigate the pathological feature of UPA in Asians
2 To clarify the relationship between pathology clinical phenotype genetic mutation and surgical outcome of UPA in Asians
3 To explore a new pathological type of unilateral primary aldosterone
2 To clarify the relationship between pathology clinical phenotype genetic mutation and surgical outcome of UPA in Asians
3 To explore a new pathological type of unilateral primary aldosterone
Detailed Description:
The multi-center expert team led by Tracy Ann Williams formulated the International Consensus on the Pathological Diagnosis of Unilateral aldehyde disease which standardized the pathological classification of unilateral PA The previous retrospective study of the research group found that the pathologic types of unilateral primary aldosteronoma were mainly classical and aldosteronoma was the most common There was no significant difference in clinical features and postoperative biochemical remission rate between patients with classic and non-classic but the clinical prognosis of the latter group was worse than that of the classical group However the study was retrospective and there may be inclusion bias The pathologic distribution and clinical features of unilateral aldehyde disease are not completely clear and need to be discussed in prospective studiesThereforethis study aims to determine the composition ratio of different pathological types in patients with unilateral procaldosis enrolled in our center Gene mutation of different pathological types the relationship between pathology and clinical phenotype gene mutation etc
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None