Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06596174
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-11
Brief Title:
Effect of tSCS on Ankle Movement Training in Individuals With SCI
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effect of tSCS on Ankle Movement Training - Evidence From Spinal Circuitry Adaptation in Individuals With SCI
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This clinical trial explores the effectiveness of transcutaneous spinal cord stimulation tSCS a non-invasive technique in facilitating spinal circuitry adaptation in individuals with spinal cord injury SCI While epidural spinal cord stimulation eSCS has shown functional benefits its application is limited by the side effects associated with implanted electrodes tSCS which shares a similar mechanism but does not require surgery has yet to be extensively studied in large human trials
The study aims to
Determine optimal tSCS parameters for non-invasive spinal stimulation Investigate the priming effect of tSCS on spinal circuitry during machine-assisted ankle movement training
Examine the long-term clinical outcomes of combining tSCS with ankle movement training in individuals with incomplete SCI
The trial will include both healthy participants and individuals with complete and incomplete SCI using the soleus post-activation depression PAD model to evaluate spinal circuitry adaptation The results will provide insights into spinal re-adaptation and potentially introduce a novel non-invasive approach for SCI rehabilitation
The study aims to
Determine optimal tSCS parameters for non-invasive spinal stimulation Investigate the priming effect of tSCS on spinal circuitry during machine-assisted ankle movement training
Examine the long-term clinical outcomes of combining tSCS with ankle movement training in individuals with incomplete SCI
The trial will include both healthy participants and individuals with complete and incomplete SCI using the soleus post-activation depression PAD model to evaluate spinal circuitry adaptation The results will provide insights into spinal re-adaptation and potentially introduce a novel non-invasive approach for SCI rehabilitation
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None