Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06595771
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-09-04
Brief Title:
Obstructive Sleep Apnea Syndrome and Fibromiyalgia
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Incidence of Fibromyalgia in Patients with OUAS and the Effect of CPAP Treatment on Fibromiyalgia Symptom Severity
Status:
COMPLETED
Status Verified Date:
2018-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
-------------Obstructive sleep apnea syndrome OSAS is a syndrome characterized by recurrent complete apnea or partial hypopnea upper respiratory tract obstruction episodes during sleep and a decrease in blood oxygen saturation It has been suggested that nocturnal arterial desaturation in patients with OSAS is effective on pain Intermittent hypoxia and oxidative stress occur in patients with OSAS Intermittent hypoxia occurring in patients with OSAS causes increased levels of HIF-1-α and mitochondrial reactive oxygen products resulting in the formation processing and formation of central and peripheral synthesis When the literature is examined pressure-related pain threshold was measured with algometer in female patients diagnosed with sleep apnea and in the control group and it was found lower in patients with OSAS
Fibromyalgia Syndrome FMS is a clinical picture with many symptoms such as chronic widespread pain fatigue sleep disturbance cognitive dysfunction Similar sleep patterns were observed in FMS and OSAS
In addition to sleep symptoms such as the presence of a similar sleep pattern a feeling of rest and daytime sleepiness in cases of OSAS and FMS it has been suggested that these two diseases may be related to each other Studies examining the relationship between OSAS and FMS syndrome including sleep disturbance and pain symptoms are rare in the literature In the current literature there are various limitations such as insufficient number of cases significant difference between demographic characteristics such as gender ethnicity age
Therefore primary goal of this study is to investigate the association of FMS in patients diagnosed with OSAS The secondary aim is to investigate the effect of CPAP Continuous Positive Airway Pressure treatment on pain sensitivity and symptom severity functional level depression in patients diagnosed with FMS and to investigate the relationship between these parameters and polysomnographic data
Fibromyalgia Syndrome FMS is a clinical picture with many symptoms such as chronic widespread pain fatigue sleep disturbance cognitive dysfunction Similar sleep patterns were observed in FMS and OSAS
In addition to sleep symptoms such as the presence of a similar sleep pattern a feeling of rest and daytime sleepiness in cases of OSAS and FMS it has been suggested that these two diseases may be related to each other Studies examining the relationship between OSAS and FMS syndrome including sleep disturbance and pain symptoms are rare in the literature In the current literature there are various limitations such as insufficient number of cases significant difference between demographic characteristics such as gender ethnicity age
Therefore primary goal of this study is to investigate the association of FMS in patients diagnosed with OSAS The secondary aim is to investigate the effect of CPAP Continuous Positive Airway Pressure treatment on pain sensitivity and symptom severity functional level depression in patients diagnosed with FMS and to investigate the relationship between these parameters and polysomnographic data
Detailed Description:
Patients between 30-65 years of age who were diagnosed with OSAS according to American Academy of Sleep Medicine AASM criteria and who had clinical symptoms of OSAS for at least 1 year before diagnosis will be performed All OSAS patients recommended and not recommended for CPAP treatment in the sleep clinic will be evaluated according to the American Rheumatology Association ACR 1990 and 2016 criteria for FMS Patients meeting both criteria will be accepted as FMS
Demographic data and polysomnographic data of patients such as age height weight BMI occupation educational status polysomnographic data AHI min O₂ sat O₂ saturation amplt90 elapsed time and percentage sleep latency sleep efficacy REM nREM123 polysomnographic data such as times REM latency severity of OSAS will be recorded
Demographic data and polysomnographic data of patients such as age height weight BMI occupation educational status polysomnographic data AHI min O₂ sat O₂ saturation amplt90 elapsed time and percentage sleep latency sleep efficacy REM nREM123 polysomnographic data such as times REM latency severity of OSAS will be recorded
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None