Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06595407
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-10
Brief Title:
Loss of Y Chromosome in Aortic Stenosis
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Loss of Y Chromosome in Aortic Stenosis
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The most common heart valve disease in humans is aortic stenosis which is a critical narrowing of the valve through which the heart has to pump blood to the rest of the body This condition occurs in 2-3 of adults over 65 years of age and when it progresses to a severe stage leads to heart failure and need for valve replacement procedures including surgery and catheter-based replacement Aortic stenosis has a strong male predominance The purpose of this study is to evaluate whether loss of Y-chromosome from circulating blood cells in males which has been associated with TGF-beta-related fibrosis of other organs is associated with the development of aortic stenosis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None