Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06586931
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-04
Brief Title:
Accuracy of Venous Excess Ultrasound VEXUS Score Versus Central Venous Pressure in Patients With Severe Sepsis
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Accuracy of Venous Excess Ultrasound VEXUS Score Versus Central Venous Pressure to Assess Volume Status in Patients With Severe Sepsis
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
assessing septic patients with a noninvasive ultrasound protocol and earlier identification of fluid overload to help clinicians decide whether to administer supplemental fluid therapy or suspend its administration and to evaluate the possible relation between the different VExUS grades and the adverse effects of intensive fluid administration
Detailed Description:
Sepsis is a life-threatening organ dysfunction caused by a poorly regulated host response to infection Septic shock is still a leading cause of death worldwide as it can induce multi-organ failure 1
Septic shock is a subset of sepsis with manifest circulatory dysfunction intravenous fluid therapy is an essential intervention to promote hemodynamic stabilization Similarly septic patients are a very different and difficult subset in intensive care unit ICU They are vasodilated and require fluid resuscitation for optimization of venous volume and cardiac output 2
Central venous pressure measurement which has been used for ages is not the ideal monitoring technique as it does not correlate with blood volume and does not give a true representation of the response of fluid challenge 3
a venous excess Doppler ultrasound VExUS grading system are parameters for the assessment of the fluid status of the patient and organ congestion This protocol evaluates the amount of venous congestion in the abdominal organs specifically by scanning the portal hepatic and intrarenal veins Doppler interrogation of these vessels yields a specific pattern corresponding to a level of venous congestion normal mild or severe 4
Septic shock is a subset of sepsis with manifest circulatory dysfunction intravenous fluid therapy is an essential intervention to promote hemodynamic stabilization Similarly septic patients are a very different and difficult subset in intensive care unit ICU They are vasodilated and require fluid resuscitation for optimization of venous volume and cardiac output 2
Central venous pressure measurement which has been used for ages is not the ideal monitoring technique as it does not correlate with blood volume and does not give a true representation of the response of fluid challenge 3
a venous excess Doppler ultrasound VExUS grading system are parameters for the assessment of the fluid status of the patient and organ congestion This protocol evaluates the amount of venous congestion in the abdominal organs specifically by scanning the portal hepatic and intrarenal veins Doppler interrogation of these vessels yields a specific pattern corresponding to a level of venous congestion normal mild or severe 4
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None