Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06586229
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-04
Brief Title:
Screening and Management of Hyperuricemia in Patients with Chronic Medical Diseases in Assiut University Hospital
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Screening and Management of Hyperuricemia in Patients with Chronic Medical Diseases in Assiut University Hospital
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study we aimed to evaluate patients with chronic medical diseases in Assiut university hospitals for -Detection of asymptomatic hyperuricemia
Early identification of associated comorbidities
Management of indicated hyperurecimia
Early identification of associated comorbidities
Management of indicated hyperurecimia
Detailed Description:
Hyperuricemia is classically defined as a serum uric acid SUA of more than 70 mgdL in men or more than 60 mgdL in women Asymptomatic hyperuricemia is a condition where patients have elevated levels of SUA yet do not exhibit symptoms or signs of monosodium urate crystal deposition such as gout attacks urolithiasis or uric acid nephropathy SUA can be elevated 10 to 15 years before clinical manifestations of gout Up to 21 of the general population and 25 of hospitalized patients are estimated to have asymptomatic hyperuricemia
Uric acid excretion mostly occurs via the kidneys so decreased glomerular filtration rates in chronic kidney CKD patients contribute to the population increase in hyperuricemia Conversely studies suggest that hyperuricemia may contribute to CKD raising the possibility that urate-lowering therapies ULTs could be useful in slowing CKD progression There was no independent association between hyperuricemia and systemic arterial hypertension Also hyperuricemia has been reported as an independent risk factor for both coronary artery disease congestive heart failure and diabetes mellitus
So efforts should be made to recognize individuals at risk of hyperuricemia by evaluating dietary habits family history and lifestyle factors and regularly monitor SUA levels As well as management strategies including lifestyle modifications pharmacotherapy and dietary interventions to effectively control SUA and reduce the risk of associated complications
Uric acid excretion mostly occurs via the kidneys so decreased glomerular filtration rates in chronic kidney CKD patients contribute to the population increase in hyperuricemia Conversely studies suggest that hyperuricemia may contribute to CKD raising the possibility that urate-lowering therapies ULTs could be useful in slowing CKD progression There was no independent association between hyperuricemia and systemic arterial hypertension Also hyperuricemia has been reported as an independent risk factor for both coronary artery disease congestive heart failure and diabetes mellitus
So efforts should be made to recognize individuals at risk of hyperuricemia by evaluating dietary habits family history and lifestyle factors and regularly monitor SUA levels As well as management strategies including lifestyle modifications pharmacotherapy and dietary interventions to effectively control SUA and reduce the risk of associated complications
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None