Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06585878
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-27
Brief Title:
A Prospective Registry Study of Stereotactic Ablative Radiotherapy SABR for OligometastaticOligometastatic Renal Cell Carcinoma
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Study on the Efficacy and Safety of Vorolanib Combined With Cadonilimab in the Treatment of Untreated Advanced RCC Patients
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Study the efficacy and toxicity of SABR treatment for oligometastaticoligoprogressive renal cell carcinoma investigate the effectiveness and safety of SABR combined with targeted immunotherapy conduct stratified analysis to identify the optimal beneficiary population establish a biobank to screen for biomarkers and use radiomics analysis to identify characteristics of sensitive populations
Detailed Description:
This study is a non-randomized prospective registry-based trial that aims to enroll 60 patients with renal cancer who will be diagnosed and treated at our hospital between May 2024 and May 2026 Without altering the patients systemic treatment plans those who meet the inclusion criteria after MDT discussion will receive SBRT Stereotactic Body Radiation Therapy for all lesionsall metastatic lesions in addition to the guideline-recommended medications The radiotherapy plan is based on the SABR-COMET protocol and Timmermans constraints Patient data will be collected including general clinical information toxicity assessments during treatment and in the acute phase detailed imaging data regular assessments of pain and quality of life and evaluations of late radiation therapy responses
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None