Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06585800
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
None
First Post:
2024-07-04
Brief Title:
Exploring the Landscape of Somatic Mutations in Human Tissue
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Exploring the Landscape of Somatic Mutations in Human Tissue
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Every cell in the human body contains a blueprint of the body called the genome Throughout life the genome can become damaged resulting in errors mutations that can change the way cells behave and may result in diseases such as cancer Examining the mutations found the genome of both normal non-cancerous and diseased cells can give a valuable insight into the very earliest stages of cancer development
Comparing the number and type of mutations in different normal tissues is revealing new insights helping us to better understand more about why cancer develops
Comparing the number and type of mutations in different normal tissues is revealing new insights helping us to better understand more about why cancer develops
Detailed Description:
The investigators are seeking to characterise somatic mutations found in normal human tissue as well as diseased tissue These experiments have shown that a number of mutational processes previously observed in cancer cells may also be present in normal tissues By further exploring normal tissue samples from across the body the investigators will be able to better understand why certain organs are more susceptible to mutations and what underlies the mutational processes active in many different tissue types
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None