Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06585332
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-28
Brief Title:
Handgrip and Respiratory Dysfunction in HD Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Hand Grip Strength As a Screening Tool for Respiratory Dysfunction in Huntingtons Disease
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hereditary neurodegenerative diagnosis of Huntingtons disease HD is associated with a progressive deterioration of the respiratory system function This fact contributes strongly to the increased risk of aspiration pneumonia as a primary cause of death in people with HD But regularly objective monitoring of the airway system condition is in common clinical practice almost impossible for high time requirements and the need for specialized expensive devices This drives the need for a simpler and more cost-effective screening tool In recent years published studies working with all ages and genders show correlation between hand grip strength HGS and respiratory parameters As a second simple screening tool we chose a short questionnaire called the Index of pulmonary dysfunction
Detailed Description:
Goal To identify a simple method for screening respiratory muscle and cough weakness in Huntington39s Disease HD patients suitable for clinical practice
Hypothesis 1 Maximal inspiratory pressure maximal expiratory pressure and voluntary peak cough flow will be significantly correlated with maximal hand grip strength in HD patients
Hypothesis 2 Maximal inspiratory pressure maximal expiratory pressure and voluntary peak cough flow will be significantly correlated with the Index of pulmonary dysfunction in HD patients
Hypothesis 1 Maximal inspiratory pressure maximal expiratory pressure and voluntary peak cough flow will be significantly correlated with maximal hand grip strength in HD patients
Hypothesis 2 Maximal inspiratory pressure maximal expiratory pressure and voluntary peak cough flow will be significantly correlated with the Index of pulmonary dysfunction in HD patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None