Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06584149
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-08-24
Brief Title:
BAR As a Mortality Predictor in Septic AKI
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Role of Blood Urea Nitrogen to Serum Albumin Ratio in the Prediction of Mortality in Septic Acute Kidney Injury Patients
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate the prognostic value of Blood Urea Nitrogen to serum Albumin ratio in septic Acute Kidney Injury patients Follow-up will be conducted for all enrolled patients for 30 days from admission to record mortality and the cause of death
Detailed Description:
A complete medical history will be obtained from all patients including age sex comorbidities cause of sepsis and SOFA and APACHE II scores at admission
Blood samples will be collected within 24 hours of AKI diagnosis for analysis of Blood Urea Nitrogen BUN and serum Albumin levels
Blood Urea Nitrogen to serum Albumin ratio BA will be calculated by dividing the BUN of a patient by their serum Albumin levels
Laboratory parameters also will include pH lactate Lac base excess BE hemoglobin Hb platelet PLT count white blood cell WBC count bilirubin hematocrit HCT creatinine Cr serum sodium Na serum potassium K serum calcium Ca serum magnesium Mg triglyceride TG aspartate aminotransferase ALT alanine aminotransferase AST prothrombin time PT and activated partial thromboplastin time APTT values
Follow-up will be conducted for all enrolled patients for 30 days from admission to record mortality and the cause of death
Study population will be divided into survival and non-survival groups based on their 30-day survival status
Blood samples will be collected within 24 hours of AKI diagnosis for analysis of Blood Urea Nitrogen BUN and serum Albumin levels
Blood Urea Nitrogen to serum Albumin ratio BA will be calculated by dividing the BUN of a patient by their serum Albumin levels
Laboratory parameters also will include pH lactate Lac base excess BE hemoglobin Hb platelet PLT count white blood cell WBC count bilirubin hematocrit HCT creatinine Cr serum sodium Na serum potassium K serum calcium Ca serum magnesium Mg triglyceride TG aspartate aminotransferase ALT alanine aminotransferase AST prothrombin time PT and activated partial thromboplastin time APTT values
Follow-up will be conducted for all enrolled patients for 30 days from admission to record mortality and the cause of death
Study population will be divided into survival and non-survival groups based on their 30-day survival status
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None