Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06581887
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-08
Brief Title:
Defining Outcome Measures for Behavioural and Emotional Problems in Dystrophinopathies
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Defining Outcome Measures for Behavioural and Emotional Problems in Dystrophinopathies
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
D-BRAIN
Brief Summary:
Study aims to develop and to evaluate the neurophysiological and physiological response to a classical conditioning taskTo better understand how Duchenne Muscular Dystrophy DMD and Becker Muscular Dystrophy BMD impacts mental health and how to assess it Participants invited to complete questionnaires about behaviour cognitive function and social interactions complete computer tasks and have an optional MRI brain scan
Detailed Description:
The investigation aims to develop and to evaluate the neurophysiological and physiological response to a classical conditioning task which is comparable to findings that have been made in the mdx dystrophic mouse deficient in Dp427 The investigators will assess correlations between the specific DMDBMD genotype and susceptibility to conditioning as well as the relationship between conditioning and behaviouralemotional characteristics of the syndrome At the end of the study the objective is to deliver a comprehensive test battery that is suitable for use in a trial of AON delivery to improve brain function
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None