Official Title: Non-invasive Monitoring of Miscarriage
Status: RECRUITING
Status Verified Date: 2024-08
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: cfDNA is extremely useful to ascertain chromosomal causes of miscarriages at the point of miscarriage diagnosis by a simple blood test This study aims to determine the level of cell-free DNA cfDNA in early pregnancy and compare the results with those of product of conception POC testing in concordance with standard karyotyping
Detailed Description: Pregnancies achieved by assisted reproductive technologies ART are closely monitored therefore miscarriages that occur very early in the pregnancy are frequently meticulously recorded and reported On the other hand spontaneous abortion rates among naturally occurring conceptions are notoriously hard to quantify and are often overstated when using criteria from assisted reproductive technologies Additionally women who have undergone treatment with ART are a particular population with traits that can make them more vulnerable to spontaneous abortions
cfDNA would be extremely useful to ascertain chromosomal causes of miscarriages at the point of miscarriage diagnosis by a simple blood test This study aims to determine the level of cell-free DNA cfDNA in early pregnancy and compare the results with those of product of conception POC testing in concordance with standard karyotyping