Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06581432
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-30
Brief Title:
Beamion PANTUMOR-1 A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Beamion PANTUMOR-1 A Phase II Multicentre Multicohort Open-label Trial to Evaluate the Efficacy and Safety of Oral Zongertinib BI 1810631 for the Treatment of Selected HER2-mutated or OverexpressedAmplified Solid Tumours
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a study for people with advanced cancer for whom previous treatment was not successful or no treatment exists Adults aged 18 and over with advanced cancer with HER2 alterations can join the study The purpose of this study is to find out whether a medicine called zongertinib helps people with advanced cancers with HER2 alterations HER2 alterations can cause cancer Zongertinib inhibits HER2
Participants are put into 10 groups based on the type of advanced cancer and the type of HER2 alterations they have All participants take one dose of zongertinib Participants can continue the treatment as long as they benefit from it and can tolerate it
Participants visit the study site regularly During many of the visits the doctors check the size of the tumour and whether it has spread to other parts of the body During all the visits the doctors check participants health and take note of any unwanted effects
Participants are put into 10 groups based on the type of advanced cancer and the type of HER2 alterations they have All participants take one dose of zongertinib Participants can continue the treatment as long as they benefit from it and can tolerate it
Participants visit the study site regularly During many of the visits the doctors check the size of the tumour and whether it has spread to other parts of the body During all the visits the doctors check participants health and take note of any unwanted effects
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None