Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06581302
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-15
Brief Title:
Magnetic Seizure Therapy for Psychotic Disorders
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Accelerated 100Hz Magnetic Seizure Therapy for Psychotic Disorders
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This trial aims to evaluate the efficacy and safety of Magnetic Seizure Therapy MST as an augmentation of antipsychotic medications for psychosis
Detailed Description:
Psychosis is recognized as one of the largest contributors to nonfatal health loss and substantial portion of patients exhibit resistance to antipsychotics emphasizing the need for exploring non-pharmacological treatments In clinical practice Electroconvulsive therapy ECT has been shown to be generally effective in psychosis but its clinical use sometimes is limited by its cognitive side effects Magnetic Seizure Therapy MST is a novel modification of electroconvulsive therapy ECT MST offers the advantages of milder side effects on cognition a quicker return of orientation and a shorter duration of post-ictal confusion A few studies have studied the antipsychotic effect of MST Therefore the present study will plan to perform a clinical trial to compare the efficacy of MST treatment plus antipsychotics to antipsychotic medications alone among psychotic disorders in acute phase In addition whether MST treatment plus antipsychotics will bring a quicker efficacy response than antipsychotic medications alone is also of important clinical significance The present trial will plan to administer 10 sessions of MST in 2 weeks in which the patients will be randomly allocated to either receiving MSTmedications or receiving medications alone After the 2 weeks research intervention all patients will be switched to clinical routine management but kept under masked clinical assessment for 4 weeks
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None