Viewing Study NCT06581094



Ignite Creation Date: 2024-10-26 @ 3:39 PM
Last Modification Date: 2024-10-26 @ 3:39 PM
Study NCT ID: NCT06581094
Status: RECRUITING
Last Update Posted: None
First Post: 2024-08-29

Brief Title: Effects of UC-II Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation
Sponsor: None
Organization: None

Study Overview

Official Title: Effects of UC-II Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation A Randomized Single-blind Placebo-controlled Parallel-group Trial
Status: RECRUITING
Status Verified Date: 2024-07
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: This research evaluated the effects of UCII glucosamine and curcumin supplementation on knee pain and inflammation
Detailed Description: Arthritis is an inflammation of one or more joints characterized by pain stiffness especially in the early morning or after exercise swelling deformation andor reduced mobility There are many different forms of arthritis Osteoarthritis also known as degenerative arthritis is caused by abnormal damage to the cartilage at the ends of bones In some patients it is caused by injury or congenital abnormalities in the proteins that make up cartilage Generally it seems that aging an unbalanced diet and an inappropriate lifestyle are the causes of this disease

Once the cartilage tissue changes from smooth to rough or breaks into small pieces the cartilage is gradually destroyed and the normally smooth surface becomes irregular Osteoarthritis usually occurs in joints that bear weight such as the spine knees hips and back It is usually preceded by pain and symptoms of stiffness often stiffness first then pain but swelling is not always present In a small number of cases osteoarthritis can cause disability As the condition progresses the bones can become more fragmented increasing the likelihood of fractures When osteoarthritis is more severe bones can overgrow into osteophytes known as bone spurs These bone spurs can be detected with X-rays usually near degenerative cartilage in the neck or waist However these changes typically do not alter the appearance of the affected area

There are more than 28 types of peptides that make up collagen with the more common types I II and III collagen accounting for about 90 of the total Type II collagen forms joints When collagen from pork bones and other sources is cooked at high temperatures the collagen structure is destroyed becoming denatured collagen Additional supplements can only be used as general collagen and therefore cannot reduce the damage and inflammation of joint cartilage Many studies have confirmed that the use of non-denatured type II collagen UC-II can provide flexible maintenance for key parts To achieve higher efficiency and longer-lasting effects it is combined with glucosamine chondroitin and curcumin In addition to providing resistance to compression in articular cartilage it can also improve inflammation and significantly reduce pain in patients with primary osteoarthritis Therefore this research evaluated the effects of UCII glucosamine and curcumin supplementation on knee pain and inflammation

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None